In this randomized clinical trial, Curcumin Phytosome was "demonstrated to be effective as an adjuvant therapy for the treatment of psoriasis vulgaris and to significantly reduce serum levels of IL-22". The participants took 1 capsule 2X per day, totaling 1000mg per day. Lowering IL-22 (Interleukin 22, an immune cytokine), is important for those with psoriasis as it is a "risk gene and important mediator in psoriasis": 22 Again: IL-22 as a Risk Gene and Important Mediator in Psoriasis - ScienceDirect. Considering that psoriasis may involve an imbalanced gut barrier, curcumin may also help because it has a balancing effect on the gut barrier.
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